It has been nearly two years since I started the Rituxan infusions, my quality of life increasing with each one. When I first started the infusions my vectra score was a 58. Which meant my disease activity was severe. My most recent blood work shows my vectra score at a 3. Down 55 points. Yes my teeth are paying the price and a bit of hair loss. When I started this journey I was pushing about 360 and on outings sometimes needed a wheelchair or cane. I eventually had gastric bypass, but the weight loss did not help my jont pain. I had tried all sorts of injections, the newest pills. Nothing worked. Then I started the Rituximab infusions. Game changer. I can now play with my grankids unlike with my children, I sat and watched. I am now about 195 and feel better than I have in years. There are side effects, like my teeth. But I will take it any day over the pain and fatigue I felt for almost 18 years. The best advice I can give is, if you think your treatment plans are not working as you would like. Change it, talk to your doctor. If you aren’t happy with your results, look at other options. I hope and pray that you find what works for you and whatever ails you. Life is to short to live in pain.